Perspectives on Ion Channel Assembly

Perspectives on Ion Channel Assembly

The purpose of the Perspectives in General Physiology is to provide a forum where scientific uncertainties or controversies can be discussed in an authoritative, yet open manner. The Perspectives are solicited by the editors—often based on recommendations by the advisory editors or members of the editorial board, who may be asked to coordinate the process. To frame the issue, two or more expert...

Perspectives on How to Drug an Ion Channel

© 2008 Andersen The Rockefeller University Press $30.00 J. Gen. Physiol. Vol. 131 No. 5 395–397 www.jgp.org/cgi/doi/10.1085/jgp.200810012 395 The purpose of the Perspectives in General Physiology is to provide a forum where scientifi c uncertainties or controversies can be discussed in an authoritative, yet open, manner. The Perspectives are solicited by the editors — often based on recommendat...

Ion Channel Assembly: Creating Structures that Function

With advances in recombinant DNA, structural, and electrophysiological techniques, much progress has been made in understanding the structure and, in particular , the function of ion channels. Less progress has been made in resolving the cell biological events that guide the assembly and trafficking of these proteins and that have a major impact on both structure and function. The assembly of a...

Perspectives on Ion Permeation

The purpose of the Perspectives in General Physiology is to provide a forum where scientific uncertainties or controversies can be discussed in an authoritative, yet open manner. The Perspectives are solicited by the editors—often based on recommendations by the advisory editors or members of the editorial board, who may be asked to coordinate the process. To frame the issue, two or more expert...

Perspectives on Ion Permeation